Arthur Goldsipe
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Separate initial estimates with categorical covariates
Unforutunately, there's currently no way to specify different initial estimates for different categorical covariate values. I ca...
12 dagar ago | 0
| accepted
How can I create a custom sensitivity analysis for a compartmental model in symbiology?
If I'm correctly understanding what you want to do, it sounds quite similar to what you can do today with global sensitvity anal...
ungefär en månad ago | 0
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Issues in fitting a simple tumor growth model
You can use the Variants property of the fitproblem to specify initial conditions that are specific to each ID. Create one varia...
3 månader ago | 0
| accepted
Nonlinear regression of multiple datasets with different functions but wit some shared parameters between datasets
I've attached a SimBiology project (created in R2024b) that illustrates how to set up this sort of problem in SimBiology. If you...
3 månader ago | 3
Occasionally when creating a SimFunction, SimBiology returns a failure to compile error, what causes this?
This error was caused by adding a custom folder to the MATLAB path. This folder contained a function that shadowed a MATLAB finc...
4 månader ago | 0
Where is the undo/redo function in SimBiology
(Rather late) update: As of R2021a, the SimBiology Model Builder app DOES support undo. At this time (which covers through R2025...
4 månader ago | 0
Capabilities of mass action kinetics
Yes, this is exactly the sort of problem SimBiology is designed for. (I'm one of the developers of this product.) You can build ...
5 månader ago | 1
| accepted
How to use sundials solvers in threads parpool?
I'm not aware of any way to do this. The only workaround I can think of is to use a process pool instead of a thread pool.
5 månader ago | 0
| accepted
i have a problem with simbiology
It sounds like you have a bad installation. I suggest trying to reinstall.
5 månader ago | 0
integration tolerance has not met
If you can share your model or other reproduction steps, then we can likely offer better advice. In the absence of those details...
5 månader ago | 0
| accepted
PBPK model construction for radioactive probe drugs
Please read the following other posts to understand the constraints on species units: Can I use "mL/kg" and "mg/kg" for compart...
6 månader ago | 0
SimBiology: 'Integration Tolerance Not Met' error occurs when the dose start time is set later than a fixed value.
The error is due to an inability to solve the equations within the specified error tolerances. Unfortunately, I believe this is ...
6 månader ago | 0
"simulations failed when using the initial values of estimated parameters" with simbiology fitting but no error when using the same parameters/setting for sbiosimulate
It's difficult to diagnose without more information. Can you share your code either here on MATLAB Answers or privately with the...
6 månader ago | 0
Using multiple datasets to fit parameters simultaneously in SimBiology
You first need to decide whether these two concentration profiles should be treated as part of the same experiment/simulation. ...
6 månader ago | 1
| accepted
Using multiple datasets to fit parameters simultaneously in SimBiology
SimBiology users typically do this by merging the multiple datasets into a single dataset and fitting them constructing an apprp...
6 månader ago | 0
How to add digestibility in SimBiology Model Builder
I'm not sure what you mean by digestibility. The closest I know of is this SimBiology example, which implements a couple of reac...
7 månader ago | 0
Model reduction of simbiology models
Hi Paulo, The model order reduction functionality that you point to is limited to linear time-invariant systems. Most SimBiolog...
7 månader ago | 0
| accepted
How to download old version of toolbox?
I think the versions you are allowed to download depend on your license. If you go to https://www.mathworks.com/downloads/ , the...
7 månader ago | 1
| accepted
simFunction and dose Array from an input file
Ok, I think I finally understand what's going on. When you create the SimFunction, you only need to specify one "template" dose...
8 månader ago | 0
| accepted
Simbiology Model Analyzer: input error for CMAX and Partial AUC
Hi, This is a bug. The bug is triggered if you try to calculate partial areas and some of the subjects don't have enough measur...
9 månader ago | 1
| accepted
Jump species quantity then stay constant
I don't yet understand what your goal is. Can you provide more details on what behavior you want? A concrete example illustratin...
10 månader ago | 1
how to understand and set the constant and boundarycondition properties.
If the Constant property of a species is true, then the value of that species cannot change at simulation times > 0. At time = 0...
11 månader ago | 0
Unit conversion in Simbiology model
Hi, I'm a developer on the SimBiology team. I'm not sure I fully understand your question, but I'll try to answer based on my cu...
12 månader ago | 0
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How to find the sensitivity of the model output if it is a variable for repeated assignment?
The solution I generally recommend is to calculate the sensitivities yourself by manualy differentiating the repeated assignment...
12 månader ago | 0
how to handle the error 'Levenberg-Marquardt algorithm the Jacobian at BETA0 is ill-conditioned'?
It's difficult to say exactly what's going on without seeing your model and data. One explanation is that your model is not appr...
12 månader ago | 0
How to write code for repetitive process?
If I understand your question, you're asking how to create an event that fires repeatedly. I'm not sure exactly what kind of rep...
12 månader ago | 0
Investigating the effect of two covariates to an estimated parameter
Yes, you can specify multiple covariates. An example covariate expresssion would be exp(theta_fixed + theta1*covariate1 + theta2...
12 månader ago | 0
| accepted
Why are population estimated parameters values the same as individual estimated parameters values?
Without the actual project, it's difficult to say what's going on. So let me offer some potential explanations for what you're s...
12 månader ago | 0
How to simulate a drug concentration-time curve with confidence intervals?
Where did this plot come from? Without more information, we won't be able to say exactly how it was created. However, it looks ...
ungefär ett år ago | 0
| accepted
Oral Dose Not Exhibiting Absorption/Bioavailability in Simulation
Copying the answer from the comments: "Just wanted to update that I figured out a solution to the problem! I ended up creating a...
ungefär ett år ago | 0
