Main Content

Build Models

Build mechanistic systems biology models or PK/PD models

Build QSP, PBPK, PK/PD, and systems biology models graphically using a block diagram editor or programmatically using MATLAB® functions. Use doses to model various dosing regimens and use variants to represent biological variability and what-if scenarios.

Apps

SimBiology Model BuilderBuild QSP, PK/PD, and mechanistic systems biology models interactively
SimBiology Model AnalyzerAnalyze QSP, PK/PD, and mechanistic systems biology models

Functions

sbiomodelConstruct model object
sbiorootReturn SimBiology root object
sbioresetDelete all model objects
sbioselectSearch for objects with specified constraints
sbiodiffCompare SimBiology models and diagram information
getComponentsGet model components associated with SimBiology model comparison results
addcompartmentCreate compartment object
addCompartmentAdd compartment to PKModelDesign object
addobservableAdd observable object to SimBiology model
addspeciesCreate species object and add to compartment object within model object
addparameterCreate parameter object and add to model or kinetic law object
addreactionCreate reaction object and add to model object
addruleCreate rule object and add to model object
addeventAdd event object to model object
constructConstruct SimBiology model from PKModelDesign object

Objects

expand all

ModelModel and component information
ObservableObject containing expression for post-simulation calculations
CompartmentObject containing compartment information
SpeciesObject containing species information
ParameterParameter and scope information
ReactionObject containing model reaction information
KineticLawKinetic law information for reaction
RuleHold rule for species and parameters
EventStore event information
RootHold models, unit libraries, and abstract kinetic law libraries
SimBiology.DiffResults Results of comparison between two SimBiology models and diagrams
PKModelDesign objectHelper object to construct pharmacokinetic model
PKCompartment objectUsed by PKModelDesign to create SimBiology model
PKModelMap objectDefine SimBiology model components’ roles

Topics

Model Building

Model Definitions