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how to automatically segment the ventricle of the brain ?

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Please help me, I need to segment the ventricle of the brain as in this example :
segventricule.PNG
I used region growth but it does not give a good result

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Image Analyst
Image Analyst on 24 Mar 2019
Edited: Image Analyst on 24 Mar 2019
If simple thresholding and spatial cleanup (like bwareafilt) doesn't work, then try some of the more sophisticated algorithms in Vision Bibliography
See attached example

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