How to detect lesions in diabetic retinopathy especially microaneurysm

I was trying to detect lesions in DR. I tried to calculate using intensity values. But my output is like regional maximum. I don't know the correct method. Please can anyone help me with methods

Answer 1

[Image Analyst]

We don't do complicated algorithm development here. I suggest you find similar methods in published papers here: http://www.visionbib.com/bibliography/contentsmedical.html#Medical%20Applications,%20CAT,%20MRI,%20Ultrasound,%20Heart%20Models,%20Brain%20Models