SimBiology model for Target-Mediated Drug Disposition (TMDD)

SimBiology implementation of the Target-Mediated Drug Disposition (TMDD) model
Updated 7 Apr 2022

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This is the SimBiology implementation of generic Target-Mediated Drug Disposition model (TMDD) presented in [1].
[1] Mager DE and Jusko WJ (2001) General pharmacokinetic model for drugs exhibiting target-mediated drug disposition. J Pharmacokinetics and Pharmacodynamics 28: 507–532.

Cite As

Fulden Buyukozturk (2024). SimBiology model for Target-Mediated Drug Disposition (TMDD) (, MATLAB Central File Exchange. Retrieved .

MATLAB Release Compatibility
Created with R2022a
Compatible with R2020b and later releases
Platform Compatibility
Windows macOS Linux
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Version Published Release Notes

Updated release compatibility

Updated release compatibility.


- Updated to work with newer versions of SimBiology.
- Added a Dose to model a daily dosing schedule and updated the scan program accordingly.

Updated license