How to get rid of "Integration Tolerance Not Met"?
7 views (last 30 days)
Show older comments
I'm trying to run a simulation of a repressilator in E. coli and get the error message above. How would you recommend I fix this issue? I have already tried messing with the simulation settings, but no luck. Thanks so much.
0 Comments
Answers (1)
Arthur Goldsipe
on 6 Apr 2021
If you simulate from the command line, you should see a warning that infinite or NaN (not-a-number) values occur during the simulation. (In R2021a you should also see these warnings in the SimBiology Model Analyzer app.)
This typically indicates a modeling error. I suggest decreasing the simulation time to something shorter and inspecting the results to make sure they make sense. I see that the value of "LacI mRNA" becomes negative after the first time step. And if I look at the reactions involving this species, the reactions rates don't look physically meaningful to me: "LacI mRNA" is consumed even when its concentration is 0.
0 Comments
Communities
More Answers in the SimBiology Community
See Also
Categories
Find more on Scan Parameter Ranges in Help Center and File Exchange
Products
Community Treasure Hunt
Find the treasures in MATLAB Central and discover how the community can help you!
Start Hunting!