how can i connect betwee eigenvalues and image ?

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in my work i have several fMRI brain images for Alzheimer Disease. and i get these images and compare between each part in these images to get the parts that are different between positive and negative images. how can i get these parts? i want to use PCA to get eigenvalues that they are the principle component of these images but how can i say this eigenvalue for this part in this image?

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