How to create a GUI

There are multiple ways to create a graphical user interface (GUI) in Matlab. Which method is the best depends on multiple factors: the complexity of the project, to what extent it should be a long-term solution, on what releases your GUI should work, your available time, your skill level, and probably other factors I'm forgetting.

To keep the thread clear I'll attempt to provide a short outline a few ways in this question, and leave the details for the answers. (@anyone with editing privileges: feel free to update the section below if I missed something important and am slow in editing this question)

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GUIDE

GUIDE is probably the first tool new users will encounter. It is very useful for quickly putting something together, but it is otherwise fairly limited. It requires maintaining (and distributing) both a .m and a .fig file. Note that the GUIDE environment will be removed in a future release. After GUIDE is removed, existing GUIDE apps will continue to run in Matlab but they will not be editable in GUIDE. If you're starting a new GUI, don't use GUIDE. If you're updating an existing GUIDE GUI, migrate it to AppDesigner. In R2021a the first step for this removal was taken: all templates except the blank template have been removed.

GUILT

Although I haven't had a detailed look myself, it seems a list like this is not complete without at least mentioning the GUI Layout Toolbox, which is available on the file exchange and offers a lot of customization options.

Programmatic GUIs

You can bypass GUIDE and use the normal figures and functions like uicontrol to build GUIs from code. This makes the design less visual, but more flexible for future additions.

App Designer

The official successor to GUIDE, AppDesigner is not based on functions, but works similar to a class. It uses uifigure and mostly uses graphical elements that are incompatible with 'normal' GUIs that are created with a figure (or .fig).